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Effect of other drugs on Cialis In Uae Price

Cialis Online Miglior Prezzo is mainly metabolized with the participation of the CYP3A4 isoenzyme. Selective inhibitor of CYP3A4, ketoconazole (400 mg/day) increases the AUC of Cialis Online Kopen Belgie in a single dose by 312% and SMACNA 22%, and ketoconazole (200 mg/day) increases the AUC of Can You Buy Cialis Over The Counter Yet in a single dose by 107% and Smachna 15% relative to the AUC values for Cialis In Uae Price Smartelco one. Ritonavir (200 mg 2 times a day), an inhibitor of isoenzymes CYP3A4, 2C9, 2C19 and 2D6, increases the AUC of Cialis In Uae Price in a single dose by 124% without changing Cmax. Although no specific interactions have been studied, it can be assumed that other HIV protease inhibitors such as saquinavir and CYP3A4 isoenzyme inhibitors such as erythromycin and Itraconazole increase Cialis In Uae Price activity.

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Side effects and overdose

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Mechanism of action

The active substance of Cialis Farmacia Online España is Cialis In Uae Price, which contributes to the inhibition of the production of the enzyme phosphodiesterase type 5 (PDE5). The enzyme (PDE5) regulates the concentration of cGMP (cyclic guanosine monophosphate) in the smooth muscles of the penis's tricky body.

After taking the pill, the concentration of cGMP increases to normal, which creates conditions for a full, healthy erection with sexual arousal. After the act of love, the penis, as expected, relaxes.

The highest concentration of the substance in the blood occurs approximately 2 hours after taking Cialis In Uae Price.

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The duration of the generic Cialis In Uae Price reaches 36 hours, but it is recommended to take a 20mg tablet 30 minutes before the intended sexual intercourse. Drink Cialis In Uae Price should be water.

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Clinical pharmacology

Several studies have been conducted to assess the effect of daily Buy Cialis Mumbai on spermatogenesis. None of the studies showed an undesirable effect on the morphology of sperm and their mobility. One study found a decrease in the average sperm concentration compared to placebo. A decrease in sperm concentration was associated with a higher ejaculation rate. In addition, there was no undesirable effect on the average concentration of sex hormones, testosterone, LH and FSH when taking Cialis In Uae Price compared to placebo.

The efficacy and safety of Cialis Malaysia Where To Buy (at doses of 2.5 mg and 5 mg) was studied in clinical trials. There was an improvement in erection in patients with erectile dysfunction of all degrees of severity when taking Cialis Buy South Africa 1 time per day. In studies of the primary efficacy of Cialis Ireland To Buy at a dose of 5 mg, 62% and 69% of sexual intercourse attempts were successful compared to 34% and 39% of placebo patients. Taking Cialis In Uae Price at a dose of 5 mg significantly improved erectile function for 24 hours between doses.

The mechanism of action of Cialis In Uae Price in patients with BPH — inhibition of PDE-5 Cialis In Uae Price, leading to an increase in the concentration of cGMP in the cavernous body of the penis, is also observed in the smooth muscles of the prostate, bladder and blood vessels that supply them. Relaxation of the smooth muscles of the vessels leads to an increase in blood perfusion in these organs and as a consequence — to reduce the severity of symptoms of BPH. Relaxation of the smooth muscles of the prostate and bladder can further enhance vascular effects.

The use of Cialis In Uae Price Cialis In Uae Price according to ED.For patients with frequent sexual activity (more than 2 times a week): the recommended frequency of intake is daily, 1 time per day 5 mg, at the same time, regardless of food intake. The daily dose may be reduced to 2.5 mg depending on individual sensitivity.

For patients with infrequent sexual activity (at least 2 times a week): it is recommended to prescribe Cialis In Uae Price at a dose of 20 mg, immediately before sexual activity, according to the instructions for medical use of Cialis Online Miglior Prezzo. The maximum daily dose of Cialis In Uae Price is 20 mg.

The use of Cialis In Uae Price Cialis In Uae Price for indication of BPH or ED/BPH.The recommended dose of Cialis Online Kaufen österreich when used once a day is 5 mg; Cialis In Uae Price should be taken at approximately the same time of day, regardless of the time of sexual activity. The duration of treatment is set by the doctor individually. In patients with renal insufficiency of mild severity (creatinine Cl from 51 to 80 ml/min) and moderate severity (creatinine Cl from 31 to 50 ml/min) dose adjustment is not required.

In patients with severe renal insufficiency (Creatinine CL <30 ml/min and hemodialysis):the use of Cialis 5mg Price In Uae once a day is not recommended.

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