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Cialis (tadalafil)

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Cialis 20 Mg Price Uae is a reversible selective inhibitor of specific PDE-5 cGMP. When sexual arousal causes local release of nitric oxide, inhibition of PDE-5 by Cialis 20 Mg Price Uae leads to an increase in the concentration of cGMP in the cavernous body of the penis. The consequence of this is the relaxation of the smooth muscles of the arteries and blood flow to the tissues of the penis, which causes an erection. Cialis 20 Mg Price Uae has no effect in the absence of sexual arousal.


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Cialis 20 Mg Price Uae has systemic vasodilating properties and can enhance the effect of antihypertensive drugs aimed at reducing blood PRESSURE.

In addition, patients who took several antihypertensive drugs, in which hypertension was poorly controlled, there was a slightly greater decrease in blood PRESSURE. In the vast majority of patients, this decrease was not associated with hypotensive symptoms. Patients receiving treatment with antihypertensive drugs and taking Cialis Price In Uae Dirham should be given appropriate clinical recommendations.

Did not observed a significant reduction in blood pressure in the application of Cialis 20mg Price In Uae in healthy individuals taking selective альфа1А-blocker tamsulosin on the results of two clinical studies.

Coadministration of Cialis 20 Mg Price Uae with doxazosin is contraindicated. When using Cialis 20 Mg Price Uae healthy volunteers, taking doxazosin (4-8 mg/day), alfa1-adrenoblokator, there was an increase in the hypotensive effect of doxazosin. Some patients experienced symptoms associated with a decrease in blood PRESSURE, including fainting.

Cialis 20 Mg Price Uae did not affect the concentration of alcohol, nor did alcohol affect the concentration of Cialis 20 Mg Price Uae. At high doses of alcohol (0.7 g/kg), Cialis 20 Mg Price Uae did not cause a statistically significant decrease in the average blood PRESSURE. Some patients had postural dizziness and orthostatic hypotension. When taking Cialis 20 Mg Price Uae in combination with lower doses of alcohol (0.6 g/kg), a decrease in blood PRESSURE was not observed, and dizziness arose with the same frequency as when taking one alcohol.

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Recommendations and contraindications

Be sure to consult your doctor before taking Cialis 20 Mg Price Uae pills. Based on your medical history, it will determine the risks you may be exposed to after taking the medicine. Here are the most important rules to follow:

  • Like any other drug of this action, Can You Buy Cialis Over The Counter is contraindicated in combination with nitrates (which are in medicines for the treatment of cardiovascular diseases).
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Side effects and overdose

Due to the well-studied experience of Cialis 20 Mg Price Uae, side effects are quite rare. But there are exceptions to the rule, so you need to be prepared for the following symptoms:

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When overdosed, the risk of getting one of the side effects increases. Therefore, you should immediately consult a doctor to conduct standard symptomatic therapy.

Mechanism of action

The active substance of Cialis 20 Mg Price Uae is Cialis 20 Mg Price Uae, which contributes to the inhibition of the production of the enzyme phosphodiesterase type 5 (PDE5). The enzyme (PDE5) regulates the concentration of cGMP (cyclic guanosine monophosphate) in the smooth muscles of the penis's tricky body.

After taking the pill, the concentration of cGMP increases to normal, which creates conditions for a full, healthy erection with sexual arousal. After the act of love, the penis, as expected, relaxes.

The highest concentration of the substance in the blood occurs approximately 2 hours after taking Cialis 20mg Price In Uae.

Rules of admission

The duration of the generic Buy Cialis Over The Counter Canada reaches 36 hours, but it is recommended to take a 20mg tablet 30 minutes before the intended sexual intercourse. Drink Cialis Malaysia Where To Buy should be water.

Per day is allowed to take no more than 40mg, the optimal dose — 1 tablet 20mg. And, as before taking any other medication, you should carefully study the instructions, namely the indications and contraindications.

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Clinical pharmacology

Cialis Generico Online Mexico is a reversible selective inhibitor of specific PDE-5 cGMP. When sexual arousal causes local release of nitric oxide, inhibition of PDE-5 by Cialis 20 Mg Price Uae leads to an increase in the concentration of cGMP in the cavernous body of the penis. The consequence of this is the relaxation of the smooth muscles of the arteries and blood flow to the tissues of the penis, which causes an erection. Cialis 20 Mg Price Uae has no effect in the absence of sexual arousal.

In vitro studies have shown that Cialis Generico Online Miglior Prezzo is a selective PDE-5 inhibitor. PDE-5 is an enzyme found in the smooth muscles of the cavernous body, in the smooth muscles of the vessels of the internal organs, in skeletal muscles, platelets, kidneys, lungs and cerebellum. The effect of Cialis 20 Mg Price Uae on PDE-5 is more active than on other PDES. Cialis 20 Mg Price Uae is 10,000 times more powerful against PDE-5 than against PDE-1, PDE-2, PDE-4 and PDE-7, which are localized in the heart, brain, blood vessels, liver, leukocytes, skeletal muscles and other organs. Cialis In Uae is 10,000 times more active in blocking PDE-5 than PDE-3, an enzyme that is found in the heart and blood vessels. This selectivity for PDE-5 versus PDE-3 is important because PDE-3 is an enzyme involved in cardiac muscle contraction. In addition, Cialis 20 Mg Price Uae is approximately 700 times more active against PDE-5 than against PDE-6, which is found in the retina and is responsible for photo transmission. Cialis 20 Mg Price Uae is also showing the action in 9000 times more potent against PDE-5 compared with its effect on PDE-8, PDE-9, PDE-10 and 14 times more potent against PDE-5 compared to PDE-11. Tissue distribution and physiological effects of PDE-8 — PDE-11 inhibition have not yet been clarified.

Cialis Uae improves erection and increases the possibility of a full sexual intercourse.

Cialis 20 Mg Price Uae in healthy individuals does not cause a significant change in sad and dad in comparison with placebo in the supine position (the average maximum decrease is 1.6/0.8 mm Hg. art respectively) and standing (mean maximum decrease of 0.2/4.6 mm Hg. art., respectively). Cialis 20 Mg Price Uae does not cause a significant change in heart rate.

Cialis Farmacia Online España does not cause changes in color recognition (blue/green), due to the low affinity for PDE-6. In addition, there is no effect of Cialis 20 Mg Price Uae on visual acuity, electroretinogram, intraocular pressure and pupil size.

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