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Cialis Farmacia Online España is mainly metabolized by the enzyme CYP3A4. Selective inhibitor CYP3A4 ketoconazole increases AUC by 107%, and rifampicin reduces it by 88%. Although specific interactions have not been studied, it can be assumed that protease inhibitors such as ritonavir and saquinavir, as well as CYP3A4 inhibitors such as erythromycin and Itraconazole, increase the activity of Cialis Farmacia Online España. The simultaneous administration of antacid (magnesium hydroxide/aluminium hydroxide) and Cialis Farmacia Online España reduced the rate of absorption of the latter without changing the AUC. Cialis Farmacia Online España enhances the hypotensive effect of nitrates. This is due to the additive effect of nitrates and Cialis Farmacia Online España on the metabolism of nitric oxide and cGMP. Therefore, the use of Cialis Farmacia Online España in patients receiving nitrates is contraindicated


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Tablets are used inside and washed down with water, regardless of the meal. The minimum time before presumable sexual intercourse has to make 20 minutes. Most often, doctors recommend a dose of 20 mg. After that, for 36 hours, you can at any moment be in full sexual readiness. The maximum frequency of admission should not exceed 1 time per day. For the elderly, no changes in the dosage and application does not exist.

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Inside. Use of Cialis Online Kaufen österreich Cialis De Vanzare Online according to the indication of erectile dysfunction (ED). For patients with frequent sexual activity (more than 2 times a week): the recommended frequency of intake is daily, 1 time per day 5 mg, at the same time, regardless of food intake. The daily dose can be reduced to 2.5 mg, depending on individual sensitivity. For patients with infrequent sexual activity (at least 2 times a week): it is recommended to prescribe Cialis Farmacia Online España at a dose of 20 mg, immediately before sexual activity, according to the instructions for medical use of Where Can I Buy Cialis Over The Counter Usa. The maximum daily dose of Cialis Farmacia Online España is 20 mg. the Use of Cialis Farmacia Online España according to the indication of BPH or ED/BPH. The recommended dose of Buy Lilly Cialis Uk when used once a day is 5 mg; Cialis Farmacia Online España should be taken at approximately the same time of day, regardless of the time of sexual activity. The duration of treatment is set by the doctor individually. In patients with mild renal insufficiency (creatinine Cl from 51 to 80 ml/min) and moderate (creatinine Cl from 31 to 50 ml/min) dose adjustment is not required. In patients with severe renal failure (Creatinine CL <30 ml/min and hemodialysis): use of Buy Liquid Cialis is contraindicated.

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Most often: headache, dyspepsia. Possible: back pain, myalgia, nasal congestion, blood flow to the face. Rarely: swelling of the eyelids, pain in the eyes, conjunctival hyperemia, dizziness.

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Symptoms: with a single appointment to healthy individuals Cialis Farmacia Online España at a dose of up to 500 mg and patients with erectile dysfunction - repeatedly up to 100 mg/day, the undesirable effects were the same as when using Cialis Price In Uae in lower doses. Treatment: in case of overdose, standard symptomatic treatment is necessary. In hemodialysis Cialis Farmacia Online España practically displayed.

Interaction with other drugs

Cialis Kuala Lumpur Online is mainly metabolized by the enzyme CYP3A4. Selective inhibitor CYP3A4 ketoconazole increases AUC by 107%, and rifampicin reduces it by 88%. Although specific interactions have not been studied, it can be assumed that protease inhibitors such as ritonavir and saquinavir, as well as CYP3A4 inhibitors such as erythromycin and Itraconazole, increase the activity of Cialis Farmacia Online España. The simultaneous administration of antacid (magnesium hydroxide/aluminium hydroxide) and Cialis Farmacia Online España reduced the rate of absorption of the latter without changing the AUC. Cialis Farmacia Online España enhances the hypotensive effect of nitrates. This is due to the additive effect of nitrates and Cialis Farmacia Online España on the metabolism of nitric oxide and cGMP. Therefore, the use of Cialis Farmacia Online España in patients receiving nitrates is contraindicated

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On sale Cialis Farmacia Online España first appeared in 2003 and immediately attracted the attention of the target audience: at that time, many wanted to buy not viagra and Cialis Farmacia Online España. As a result, the sale soon appeared exact copies of Cialis Buy South Africa — generics, which accurately repeated the composition of the original substance, but cost much less.

Whether it is possible to buy generic Cialis Online Kaufen Ohne Rezept, whether it will harm health — similar thoughts arise in many who want to buy Cialis Farmacia Online España. I must say that such doubts are in vain, as Cialis Farmacia Online España-copy passes the same tests and tests as the original. In addition, the branded drug is quite expensive, and not everyone can buy it.

The effect on the body Cialis Farmacia Online España is similar to Viagra and similar drugs, but there are some significant differences. For example, the action of Cialis Farmacia Online España is based on the properties of Cialis Online Italia Consegna Veloce, which affects blood circulation in the pelvic organs, and the work of this substance continues for 36 hours, which is a record for today (for comparison: the duration of viagra is about 6 hours).

The long-term effect of Cialis Online San Marino allows you not to worry about what you need to do everything in time: taking a pill, a man will be able to quality sexual intercourse within 1.5 days.

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Many men want to buy generic Cialis Online Miglior Prezzo, not viagra, as in parallel with taking the pill you can drink alcohol and eat (even fat) without any health consequences. In addition, Cialis Farmacia Online España does not serve as a reason for excitement, but only normalizes erectile function, allowing men to lead a full sexual life.

In addition, clinical trials have shown that men who underwent therapeutic treatment with Cialis Farmacia Online España, noticed an improvement in erection and after taking generic.

Pharmacological action

Cialis Farmacia Online España for the treatment of erectile dysfunction. Cialis Farmacia Online España is a reversible selective inhibitor of cyclic guanosine monophosphate (cGMP) PDE5. When sexual arousal causes local release of nitric oxide, inhibition of PDE5 by Cialis Farmacia Online España leads to an increase in the concentration of cGMP in the cavernous body of the penis. The consequence of this is the relaxation of the smooth muscles of the arteries and blood flow to the tissues of the penis, which causes an erection. Cialis Farmacia Online España has no effect in the absence of sexual arousal.

In vitro studies have shown that Cialis Farmacia Online España is a selective PDE5 inhibitor. PDE5 is an enzyme found in the smooth muscles of the cavernous body, in the smooth muscles of the vessels of the internal organs, in skeletal muscles, platelets, kidneys, lungs and cerebellum. The effect of Cialis Farmacia Online España on PDE5 is more active than on other PDES. Cialis Farmacia Online España is 10,000 times more potent against PDE5 than against PDE1, PDE2, PDE4 and PDE7, which are localized in the heart, brain, blood vessels, liver, leukocytes, skeletal muscles and other organs. Cialis Farmacia Online España is 10,000 times more active in blocking PDE5 than PDE3, an enzyme that is found in the heart and blood vessels. This selectivity concerning PDE5 compared to ФДЭ3 is important because ФДЭ3 is an enzyme participating in the reduction of cardiac muscle. In addition, Cialis Farmacia Online España is approximately 700 times more active against PDE5 than against PDE6 found in the retina and responsible for photo transmission. Cialis 5 Mg Online Italia is also showing the action in 9000 times more potent against PDE5 compared to its effect on PDE8, PDE9 and PDE10, and 14 times more potent against PDE5 compared to PDE11. Tissue distribution and physiological effects of inhibition of PDE8 - PDE11 have not yet been clarified.

Cialis Farmacia Online España improves erection and increases the possibility of a full sexual intercourse.

Cialis Farmacia Online España in healthy individuals does not cause a significant change in systolic and diastolic pressure in comparison with placebo in the supine position (the average maximum decrease is 1.6/0.8 mm Hg. respectively) and in the standing position (the average maximum decrease is 0.2/4.6 mm Hg. art., respectively). Cialis Farmacia Online España does not cause a significant change in heart rate. Cialis Farmacia Online España does not cause changes in color recognition (blue/green), due to its low affinity for PDE6. In addition, there is no effect of Cialis Farmacia Online España on visual acuity, electroretinogram, intraocular pressure and pupil size.

Several studies have been conducted to assess the effect of daily Cialis Farmacia Online España on spermatogenesis. None of the studies showed an undesirable effect on the morphology of sperm and their mobility. One study found a decrease in the average sperm concentration compared to placebo. A decrease in sperm concentration was associated with a higher ejaculation rate. In addition, there was no undesirable effect on the average concentration of sex hormones, testosterone, LH and FSH when taking Cialis Farmacia Online España compared to placebo.

The efficacy and safety of Cialis Farmacia Online España (at doses of 2.5 mg and 5 mg) was studied in clinical trials. There was an improvement in erection in patients with erectile dysfunction of all degrees of severity when taking Cialis Farmacia Online España 1 time/day. In studies of the primary efficacy of Cialis Farmacia Online España at a dose of 5 mg, 62% and 69% of sexual intercourse attempts were successful compared to 34% and 39% of placebo patients. Cialis Farmacia Online España at a dose of 5 mg significantly improved erectile function for 24 hours between doses.

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