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In vitro studies have shown that Buy Cialis Taiwan is a selective PDE-5 inhibitor. PDE-5 is an enzyme found in the smooth muscles of the cavernous body, in the smooth muscles of the vessels of the internal organs, in skeletal muscles, platelets, kidneys, lungs and cerebellum. The effect of Buy Cialis Taiwan on PDE-5 is more active than on other PDES. Buy Cialis Discount is 10,000 times more powerful against PDE-5 than against PDE-1, PDE-2, PDE-4 and PDE-7, which are localized in the heart, brain, blood vessels, liver, leukocytes, skeletal muscles and other organs. Buy Cialis Taiwan is 10,000 times more active in blocking PDE-5 than PDE-3, an enzyme that is found in the heart and blood vessels. This selectivity for PDE-5 versus PDE-3 is important because PDE-3 is an enzyme involved in cardiac muscle contraction. In addition, Cialis Generico Online Mexico is approximately 700 times more active against PDE-5 than against PDE-6, which is found in the retina and is responsible for photo transmission. Buy Cialis Taiwan is also showing the action in 9000 times more potent against PDE-5 compared with its effect on PDE-8, PDE-9, PDE-10 and 14 times more potent against PDE-5 compared to PDE-11. Tissue distribution and physiological effects of PDE-8 — PDE-11 inhibition have not yet been clarified.

Cialis Online Consegna Veloce improves erection and increases the possibility of a full sexual intercourse.

Cialis Online Farmacia Italiana in healthy individuals does not cause a significant change in sad and dad in comparison with placebo in the supine position (the average maximum decrease is 1.6/0.8 mm Hg. art respectively) and standing (mean maximum decrease of 0.2/4.6 mm Hg. art., respectively). Buy Cialis Taiwan does not cause a significant change in heart rate.

Buy Cialis Taiwan does not cause changes in color recognition (blue/green), due to the low affinity for PDE-6. In addition, there is no effect of Where Can You Buy Cialis Over The Counter on visual acuity, electroretinogram, intraocular pressure and pupil size.

Effect of Buy Cialis Taiwan on other drugs

It is known that Buy Cialis Miami increases the hypotensive effect of nitrates. This is due to the additive effect of nitrates and Cialis Online Bestellen Erfahrungsberichte on the metabolism of nitric oxide (NO) and cGMP. Therefore, the use of Buy Cialis Taiwan in patients receiving nitrates is contraindicated.

Buy Cialis Taiwan does not have a clinically significant effect on the clearance of drugs whose metabolism occurs with the participation of cytochrome P450. Studies have confirmed that Buy Cialis Taiwan does not inhibit or induce isoenzymes CYP1A2, CYP3A4, CYP2C9, CYP2C19, CYP2D6, CYP2E1.

Where Can You Buy Cialis Over The Counter does not have a clinically significant effect on the pharmacokinetics of S-warfarin or R-warfarin. Buy Cialis Taiwan does not affect the action of warfarin against PV.

Cialis Veilig Online Kopen does not increase the duration of bleeding caused by acetylsalicylic acid.

Buy Cialis Taiwan has systemic vasodilating properties and can enhance the effect of antihypertensive drugs aimed at reducing blood PRESSURE.

In addition, patients who took several antihypertensive drugs, in which hypertension was poorly controlled, there was a slightly greater decrease in blood PRESSURE. In the vast majority of patients, this decrease was not associated with hypotensive symptoms. Patients receiving treatment with antihypertensive drugs and taking Buy Cialis Taiwan should be given appropriate clinical recommendations.

Did not observed a significant reduction in blood pressure in the application of Buy Cialis Taiwan in healthy individuals taking selective альфа1А-blocker tamsulosin on the results of two clinical studies.

Coadministration of Comprar Cialis Online Entrega 24 Horas with doxazosin is contraindicated. When using Buy Cialis Taiwan healthy volunteers, taking doxazosin (4-8 mg/day), alfa1-adrenoblokator, there was an increase in the hypotensive effect of doxazosin. Some patients experienced symptoms associated with a decrease in blood PRESSURE, including fainting.

Cialis Online Farmacia Italiana did not affect the concentration of alcohol, nor did alcohol affect the concentration of Buy Cialis Taiwan. At high doses of alcohol (0.7 g/kg), Buy Cialis Taiwan did not cause a statistically significant decrease in the average blood PRESSURE. Some patients had postural dizziness and orthostatic hypotension. When taking Buy Cialis Taiwan in combination with lower doses of alcohol (0.6 g/kg), a decrease in blood PRESSURE was not observed, and dizziness arose with the same frequency as when taking one alcohol.

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Recommendations and contraindications

Be sure to consult your doctor before taking Buy Cialis Taiwan pills. Based on your medical history, it will determine the risks you may be exposed to after taking the medicine. Here are the most important rules to follow:

  • Like any other drug of this action, Buy Cialis Taiwan is contraindicated in combination with nitrates (which are in medicines for the treatment of cardiovascular diseases).
  • The body, which is sensitive to any of the components of Buy Cialis Taiwan, Buy Cialis Taiwan is strictly contraindicated.
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Side effects and overdose

Due to the well-studied experience of Cialis Generico Online Italia Consegna Veloce, side effects are quite rare. But there are exceptions to the rule, so you need to be prepared for the following symptoms:

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  • Nasal congestion

When overdosed, the risk of getting one of the side effects increases. Therefore, you should immediately consult a doctor to conduct standard symptomatic therapy.

Mechanism of action

The active substance of Buy Cialis Taiwan is Buy Cialis Taiwan, which contributes to the inhibition of the production of the enzyme phosphodiesterase type 5 (PDE5). The enzyme (PDE5) regulates the concentration of cGMP (cyclic guanosine monophosphate) in the smooth muscles of the penis's tricky body.

After taking the pill, the concentration of cGMP increases to normal, which creates conditions for a full, healthy erection with sexual arousal. After the act of love, the penis, as expected, relaxes.

The highest concentration of the substance in the blood occurs approximately 2 hours after taking Buy Cialis Taiwan.

Rules of admission

The duration of the generic Buy Cialis Taiwan reaches 36 hours, but it is recommended to take a 20mg tablet 30 minutes before the intended sexual intercourse. Drink Cialis Legal Online Bestellen should be water.

Per day is allowed to take no more than 40mg, the optimal dose — 1 tablet 20mg. And, as before taking any other medication, you should carefully study the instructions, namely the indications and contraindications.

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