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Cialis (tadalafil)

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Quick Overview

Per day is allowed to take no more than 40mg, the optimal dose — 1 tablet 20mg. And, as before taking any other medication, you should carefully study the instructions, namely the indications and contraindications.


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Information

Effect of other drugs on Cialis Uae

Cialis Uae is mainly metabolized with the participation of the CYP3A4 isoenzyme. Selective inhibitor of CYP3A4, ketoconazole (400 mg/day) increases the AUC of Cialis Buy Dubai in a single dose by 312% and SMACNA 22%, and ketoconazole (200 mg/day) increases the AUC of Cialis Uae in a single dose by 107% and Smachna 15% relative to the AUC values for Cialis Farmacia Online España Smartelco one. Ritonavir (200 mg 2 times a day), an inhibitor of isoenzymes CYP3A4, 2C9, 2C19 and 2D6, increases the AUC of Cialis Uae in a single dose by 124% without changing Cmax. Although no specific interactions have been studied, it can be assumed that other HIV protease inhibitors such as saquinavir and CYP3A4 isoenzyme inhibitors such as erythromycin and Itraconazole increase Buy Cialis Over The Counter Usa activity.

Selective inducer of CYP3A4, rifampin (600 mg/day), reduces the exposure of a single dose of Cialis Uae (AUC) by 88% and SMACNA 46% relative to the AUC values for Cialis Online Italia Consegna Veloce Smartelco one. It can be assumed that the simultaneous use of other inducers of CYP3A4 isoenzyme should also reduce the concentration of Comprar Cialis Online En Usa in plasma.

Simultaneous administration of antacid (magnesium hydroxide/aluminum hydroxide) and Cialis Uae reduces the rate of absorption of Cialis Uae without changing the area under the pharmacokinetic curve for Cialis Online Miglior Prezzo. The increase in gastric pH as a result of the H2-histamine receptor blocker nizatidine had no effect on the pharmacokinetics of Can I Buy Cialis Over The Counter Australia.

The safety and effectiveness of the combination of Cialis Uae with other types of treatment of erection disorders have not been studied, so the use of such combinations is not recommended.

Cialis Uae does not potentiate the increase in bleeding time caused by taking acetylsalicylic acid.

About Cialis Uae

Cialis Uae is a drug that has long gained popularity in men who have a weak or unstable erection. A huge number of clinical studies and experiments were conducted, in which several thousand people with erectile dysfunction participated. The effectiveness of Cialis Uae was 81%, this percentage of men was able to fully restore the "normal" erection, the rest got rid of their ailments, depending on the degree of complexity of the disease. Agree, this is an amazing result!

The main feature of Cialis Uae is the ability to restore an erection for 36 hours after taking the pill, which will occur only with sexual arousal. That allows partners not to adapt to a certain time of Cialis Uae, and lead a normal life before the natural desire. In addition, the effectiveness of Cialis Uae will not affect a hearty dinner or drunk alcohol, which is also a definite plus for men of any age.

Action of preparation

We all understand that the main effect of the action of Cialis Uae should be only one – increasing potency in men. This is exactly what happens after the use of Cialis Uae, with sexual arousal: the blood vessels of the penis expand, after which it receives a more enhanced blood flow, thereby creating a "normal" erection. A noticeable improvement in potency can be observed within 20 minutes after the use of Cialis Uae.

Application and dosage

Tablets are used inside and washed down with water, regardless of the meal. The minimum time before presumable sexual intercourse has to make 20 minutes. Most often, doctors recommend a dose of 20 mg. After that, for 36 hours, you can at any moment be in full sexual readiness. The maximum frequency of admission should not exceed 1 time per day. For the elderly, no changes in the dosage and application does not exist.

Effect of Cialis Uae on other drugs

It is known that Cialis Uae increases the hypotensive effect of nitrates. This is due to the additive effect of nitrates and Cialis Uae on the metabolism of nitric oxide (NO) and cGMP. Therefore, the use of Buy Cialis Taiwan in patients receiving nitrates is contraindicated.

Cialis Uae does not have a clinically significant effect on the clearance of drugs whose metabolism occurs with the participation of cytochrome P450. Studies have confirmed that Cialis Uae does not inhibit or induce isoenzymes CYP1A2, CYP3A4, CYP2C9, CYP2C19, CYP2D6, CYP2E1.

Comprar Cialis Online En Usa does not have a clinically significant effect on the pharmacokinetics of S-warfarin or R-warfarin. Cialis Uae does not affect the action of warfarin against PV.

Cialis Uae does not increase the duration of bleeding caused by acetylsalicylic acid.

Cialis Uae has systemic vasodilating properties and can enhance the effect of antihypertensive drugs aimed at reducing blood PRESSURE.

In addition, patients who took several antihypertensive drugs, in which hypertension was poorly controlled, there was a slightly greater decrease in blood PRESSURE. In the vast majority of patients, this decrease was not associated with hypotensive symptoms. Patients receiving treatment with antihypertensive drugs and taking Cialis Uae should be given appropriate clinical recommendations.

Did not observed a significant reduction in blood pressure in the application of Cialis Uae in healthy individuals taking selective альфа1А-blocker tamsulosin on the results of two clinical studies.

Coadministration of Cialis Online Miglior Prezzo with doxazosin is contraindicated. When using Cialis Uae healthy volunteers, taking doxazosin (4-8 mg/day), alfa1-adrenoblokator, there was an increase in the hypotensive effect of doxazosin. Some patients experienced symptoms associated with a decrease in blood PRESSURE, including fainting.

Cialis Uae did not affect the concentration of alcohol, nor did alcohol affect the concentration of Cialis Uae. At high doses of alcohol (0.7 g/kg), Cialis Uae did not cause a statistically significant decrease in the average blood PRESSURE. Some patients had postural dizziness and orthostatic hypotension. When taking Cialis Uae in combination with lower doses of alcohol (0.6 g/kg), a decrease in blood PRESSURE was not observed, and dizziness arose with the same frequency as when taking one alcohol.

Cialis Buy South Africa has no clinically significant effect on the pharmacokinetics or pharmacodynamics of theophylline.

Dosage and administration

Inside. Use of Cialis Uae Cialis Uae according to the indication of erectile dysfunction (ED). For patients with frequent sexual activity (more than 2 times a week): the recommended frequency of intake is daily, 1 time per day 5 mg, at the same time, regardless of food intake. The daily dose can be reduced to 2.5 mg, depending on individual sensitivity. For patients with infrequent sexual activity (at least 2 times a week): it is recommended to prescribe Cialis Uae at a dose of 20 mg, immediately before sexual activity, according to the instructions for medical use of Cialis Uae. The maximum daily dose of Cialis Uae is 20 mg. the Use of Cialis Online Kopen Ervaringen according to the indication of BPH or ED/BPH. The recommended dose of Cialis Uae when used once a day is 5 mg; Cialis Uae should be taken at approximately the same time of day, regardless of the time of sexual activity. The duration of treatment is set by the doctor individually. In patients with mild renal insufficiency (creatinine Cl from 51 to 80 ml/min) and moderate (creatinine Cl from 31 to 50 ml/min) dose adjustment is not required. In patients with severe renal failure (Creatinine CL <30 ml/min and hemodialysis): use of Cialis Uae is contraindicated.

Side effect

Most often: headache, dyspepsia. Possible: back pain, myalgia, nasal congestion, blood flow to the face. Rarely: swelling of the eyelids, pain in the eyes, conjunctival hyperemia, dizziness.

Overdose

Symptoms: with a single appointment to healthy individuals Cialis Uae at a dose of up to 500 mg and patients with erectile dysfunction - repeatedly up to 100 mg/day, the undesirable effects were the same as when using Cialis Uae in lower doses. Treatment: in case of overdose, standard symptomatic treatment is necessary. In hemodialysis Cialis Uae practically displayed.

Interaction with other drugs

Comprare Cialis Online è Legale is mainly metabolized by the enzyme CYP3A4. Selective inhibitor CYP3A4 ketoconazole increases AUC by 107%, and rifampicin reduces it by 88%. Although specific interactions have not been studied, it can be assumed that protease inhibitors such as ritonavir and saquinavir, as well as CYP3A4 inhibitors such as erythromycin and Itraconazole, increase the activity of Cialis Uae. The simultaneous administration of antacid (magnesium hydroxide/aluminium hydroxide) and Cialis Uae reduced the rate of absorption of the latter without changing the AUC. Cialis Online Kaufen Ohne Rezept enhances the hypotensive effect of nitrates. This is due to the additive effect of nitrates and Cialis Uae on the metabolism of nitric oxide and cGMP. Therefore, the use of Cialis Uae in patients receiving nitrates is contraindicated

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