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Information

Recommendations and contraindications

Be sure to consult your doctor before taking Cialis In Uae pills. Based on your medical history, it will determine the risks you may be exposed to after taking the medicine. Here are the most important rules to follow:

  • Like any other drug of this action, Cialis 5mg Price In Uae is contraindicated in combination with nitrates (which are in medicines for the treatment of cardiovascular diseases).
  • The body, which is sensitive to any of the components of Cialis In Uae, Cialis In Uae is strictly contraindicated.
  • It should not be used by persons under the age of 18.
  • Hypertension, hepatic or renal failure, disorders of the heart-are one of the most important contraindications for the use of Cialis In Uae.

Side effects and overdose

Due to the well-studied experience of Cialis In Uae, side effects are quite rare. But there are exceptions to the rule, so you need to be prepared for the following symptoms:

  • Mild headaches
  • Dizziness and vomiting
  • A rush of blood to the face
  • Nasal congestion

When overdosed, the risk of getting one of the side effects increases. Therefore, you should immediately consult a doctor to conduct standard symptomatic therapy.

Clinical pharmacology

Several studies have been conducted to assess the effect of daily Cialis In Uae on spermatogenesis. None of the studies showed an undesirable effect on the morphology of sperm and their mobility. One study found a decrease in the average sperm concentration compared to placebo. A decrease in sperm concentration was associated with a higher ejaculation rate. In addition, there was no undesirable effect on the average concentration of sex hormones, testosterone, LH and FSH when taking Buy Cialis Super Active compared to placebo.

The efficacy and safety of Cialis In Uae (at doses of 2.5 mg and 5 mg) was studied in clinical trials. There was an improvement in erection in patients with erectile dysfunction of all degrees of severity when taking Cialis In Uae 1 time per day. In studies of the primary efficacy of Cialis Online Snabb Leverans at a dose of 5 mg, 62% and 69% of sexual intercourse attempts were successful compared to 34% and 39% of placebo patients. Taking Cialis In Uae at a dose of 5 mg significantly improved erectile function for 24 hours between doses.

The mechanism of action of Cialis Farmacia Online España in patients with BPH — inhibition of PDE-5 Cialis Online Bestellen Erfahrungsberichte, leading to an increase in the concentration of cGMP in the cavernous body of the penis, is also observed in the smooth muscles of the prostate, bladder and blood vessels that supply them. Relaxation of the smooth muscles of the vessels leads to an increase in blood perfusion in these organs and as a consequence — to reduce the severity of symptoms of BPH. Relaxation of the smooth muscles of the prostate and bladder can further enhance vascular effects.

The use of Cialis In Uae Cialis In Uae according to ED.For patients with frequent sexual activity (more than 2 times a week): the recommended frequency of intake is daily, 1 time per day 5 mg, at the same time, regardless of food intake. The daily dose may be reduced to 2.5 mg depending on individual sensitivity.

For patients with infrequent sexual activity (at least 2 times a week): it is recommended to prescribe Cialis In Uae at a dose of 20 mg, immediately before sexual activity, according to the instructions for medical use of Cialis In Uae. The maximum daily dose of Cialis In Uae is 20 mg.

The use of Cialis In Uae Cialis In Uae for indication of BPH or ED/BPH.The recommended dose of Cialis In Uae when used once a day is 5 mg; Cialis In Uae should be taken at approximately the same time of day, regardless of the time of sexual activity. The duration of treatment is set by the doctor individually. In patients with renal insufficiency of mild severity (creatinine Cl from 51 to 80 ml/min) and moderate severity (creatinine Cl from 31 to 50 ml/min) dose adjustment is not required.

In patients with severe renal insufficiency (Creatinine CL <30 ml/min and hemodialysis):the use of Buy Cialis Johannesburg once a day is not recommended.

Peculiar properties

On sale Cialis In Uae first appeared in 2003 and immediately attracted the attention of the target audience: at that time, many wanted to buy not viagra and Cialis In Uae. As a result, the sale soon appeared exact copies of Cialis In Uae — generics, which accurately repeated the composition of the original substance, but cost much less.

Whether it is possible to buy generic Cialis In Uae, whether it will harm health — similar thoughts arise in many who want to buy Cialis Generico Online Mexico. I must say that such doubts are in vain, as Cialis In Uae-copy passes the same tests and tests as the original. In addition, the branded drug is quite expensive, and not everyone can buy it.

The effect on the body Cialis In Uae is similar to Viagra and similar drugs, but there are some significant differences. For example, the action of Cialis In Uae is based on the properties of Cialis Online Kopen Belgie, which affects blood circulation in the pelvic organs, and the work of this substance continues for 36 hours, which is a record for today (for comparison: the duration of viagra is about 6 hours).

The long-term effect of Cialis 5 Mg Online Italia allows you not to worry about what you need to do everything in time: taking a pill, a man will be able to quality sexual intercourse within 1.5 days.

What else is the argument for purchasing Cialis 5mg Daily Buy Online?

Many men want to buy generic Cialis In Uae, not viagra, as in parallel with taking the pill you can drink alcohol and eat (even fat) without any health consequences. In addition, Cialis In Uae does not serve as a reason for excitement, but only normalizes erectile function, allowing men to lead a full sexual life.

In addition, clinical trials have shown that men who underwent therapeutic treatment with Cialis In Uae, noticed an improvement in erection and after taking generic.

Pharmacokinetics

The pharmacokinetics of Cialis In Uae in patients with erectile dysfunction is similar to the pharmacokinetics of Buy Cialis In Makati in persons without erectile dysfunction.

Suction

After taking Cialis In Uae inside Cialis In Uae is rapidly absorbed. The average plasma Cmax is achieved in an average of 2 hours after ingestion. The rate and degree of absorption of Cialis Super Active Online Australia does not depend on the meal, so Cialis In Uae® can be used regardless of the meal. The time of administration (morning or evening) had no clinically significant effect on the rate and degree of absorption.

The pharmacokinetics of Cialis In Uae in healthy individuals is linear in terms of time and dose. In the dose range from 2.5 to 20 mg AUC increases in proportion to the dose.

Distribution

Css in plasma are attained within 5 days while taking Cialis In Uae 1 time/day.

The average Vd is about 63 liters, which indicates that Cialis Kaufen Online Rezeptfrei is distributed in the tissues of the body.

The plasma protein binding of Cialis In Uae at therapeutic concentrations 94%.

In healthy individuals, less than 0.0005% of the administered dose was found in sperm.

Metabolism

Cialis 20 Mg Price Uae is mainly metabolized with the participation of the CYP3A4 isoenzyme. The major circulating metabolite is methylethanolamine. This metabolite is at least 13,000 times less active against PDE5 than Cialis In Uae. Therefore, the concentration of this metabolite is not clinically significant.

Breeding

In healthy individuals, the average clearance of Cialis In Uae when administered is 2.5 l/h, and the average T1/2 - 17.5 h. Buy Cialis Johannesburg is excreted mainly in the form of inactive metabolites, mainly with feces (about 61% of the dose) and, to a lesser extent, with urine (about 36% of the dose).

Pharmacokinetics in special clinical cases

Binding to proteins does not change with impaired renal function.

Healthy elderly patients (65 years and more) had a lower clearance of Cialis In Uae when administered, which was expressed in an increase in AUC by 25% compared with healthy individuals aged 19 to 45 years. This difference is not clinically significant and does not require dose adjustment.

In patients with renal insufficiency of mild to moderate severity dose adjustment is not required. Due to the increased exposure of Cialis In Uae (AUC), patients with severe renal insufficiency are not recommended to use Cialis In Uae®.

The pharmacokinetics of Buy Cialis Discount in patients with weak and moderate hepatic insufficiency is comparable to that in healthy individuals In patients with severe hepatic insufficiency (class C according to the child-Pugh classification) data are not available. When prescribing Comprar Cialis Online Em Portugal Cialis Online Kaufen Schweiz® patients with severe liver failure must first assess the risk and benefit of Cialis In Uae.

In patients with diabetes mellitus during the use of Cialis In Uae AUC was less by about 19% than in healthy individuals. This difference does not require dose selection.

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