Home
Currency:USD
Language: en

ED RX Medications

0
You have no items in your shopping cart.

0

Currency: USD
Language: English

Welcome to our online pharmacy!

Cialis (tadalafil)

Cialis (tadalafil)

$ 1.25 per pill

Quick Overview

It is known that Cialis Uae increases the hypotensive effect of nitrates. This is due to the additive effect of nitrates and Cialis Uae on the metabolism of nitric oxide (NO) and cGMP. Therefore, the use of Cialis Uae in patients receiving nitrates is contraindicated.

Cialis Uae does not have a clinically significant effect on the clearance of drugs whose metabolism occurs with the participation of cytochrome P450. Studies have confirmed that Cialis Uae does not inhibit or induce isoenzymes CYP1A2, CYP3A4, CYP2C9, CYP2C19, CYP2D6, CYP2E1.

Cialis Uae does not have a clinically significant effect on the pharmacokinetics of S-warfarin or R-warfarin. Cialis Uae does not affect the action of warfarin against PV.


Cialis: Tazalis (Axon Pharma Pvt. Ltd.), Tadalista (Dadha Pharma Pvt. Ltd.)

Cialis (Tadalafil) 80 mg

Cialis
Tadalafil
80 mg x 180 pills
$ 522.90 $ 496.95
$ 2.76 per pill
Buy
Cialis
Tadalafil
80 mg x 120 pills
$ 382.90 $ 363.95
$ 3.03 per pill
Buy
Cialis
Tadalafil
80 mg x 90 pills
$ 334.90 $ 317.95
$ 3.53 per pill
Buy
Cialis
Tadalafil
80 mg x 60 pills
$ 256.90 $ 243.95
$ 4.07 per pill
Buy
Cialis
Tadalafil
80 mg x 30 pills
$ 145.90 $ 137.95
$ 4.60 per pill
Buy
Cialis
Tadalafil
80 mg x 20 pills
$ 106.90 $ 100.95
$ 5.05 per pill
Buy
Cialis
Tadalafil
80 mg x 10 pills
$ 63.90 $ 59.95
$ 6.00 per pill
Buy

Cialis (Tadalafil) 60 mg

Cialis
Tadalafil
60 mg x 180 pills
$ 473.90 $ 450.95
$ 2.51 per pill
Buy
Cialis
Tadalafil
60 mg x 120 pills
$ 357.90 $ 339.95
$ 2.83 per pill
Buy
Cialis
Tadalafil
60 mg x 90 pills
$ 295.90 $ 280.95
$ 3.12 per pill
Buy
Cialis
Tadalafil
60 mg x 60 pills
$ 224.90 $ 212.95
$ 3.55 per pill
Buy
Cialis
Tadalafil
60 mg x 30 pills
$ 134.90 $ 127.95
$ 4.26 per pill
Buy
Cialis
Tadalafil
60 mg x 20 pills
$ 99.90 $ 93.95
$ 4.70 per pill
Buy
Cialis
Tadalafil
60 mg x 10 pills
$ 55.90 $ 51.95
$ 5.20 per pill
Buy

Cialis (Tadalafil) 40 mg

Cialis
Tadalafil
40 mg x 180 pills
$ 504.90 $ 479.95
$ 2.67 per pill
Buy
Cialis
Tadalafil
40 mg x 120 pills
$ 357.90 $ 339.95
$ 2.83 per pill
Buy
Cialis
Tadalafil
40 mg x 90 pills
$ 292.90 $ 277.95
$ 3.09 per pill
Buy
Cialis
Tadalafil
40 mg x 60 pills
$ 211.90 $ 200.95
$ 3.35 per pill
Buy
Cialis
Tadalafil
40 mg x 30 pills
$ 114.90 $ 108.95
$ 3.63 per pill
Buy
Cialis
Tadalafil
40 mg x 20 pills
$ 81.90 $ 76.95
$ 3.85 per pill
Buy
Cialis
Tadalafil
40 mg x 10 pills
$ 45.90 $ 42.95
$ 4.29 per pill
Buy

Cialis (Tadalafil) 20 mg

Cialis
Tadalafil
20 mg x 360 pills
$ 504.90 $ 479.95
$ 1.33 per pill
Buy
Cialis
Tadalafil
20 mg x 270 pills
$ 402.90 $ 382.95
$ 1.42 per pill
Buy
Cialis
Tadalafil
20 mg x 180 pills
$ 300.90 $ 285.95
$ 1.59 per pill
Buy
Cialis
Tadalafil
20 mg x 120 pills
$ 221.90 $ 210.95
$ 1.76 per pill
Buy
Cialis
Tadalafil
20 mg x 90 pills
$ 194.90 $ 184.95
$ 2.05 per pill
Buy
Cialis
Tadalafil
20 mg x 60 pills
$ 149.90 $ 141.95
$ 2.37 per pill
Buy
Cialis
Tadalafil
20 mg x 30 pills
$ 85.90 $ 80.95
$ 2.70 per pill
Buy
Cialis
Tadalafil
20 mg x 20 pills
$ 62.90 $ 58.95
$ 2.95 per pill
Buy
Cialis
Tadalafil
20 mg x 10 pills
$ 37.90 $ 34.95
$ 3.50 per pill
Buy

Cialis (Tadalafil) 10 mg

Cialis
Tadalafil
10 mg x 360 pills
$ 473.90 $ 450.95
$ 1.25 per pill
Buy
Cialis
Tadalafil
10 mg x 270 pills
$ 378.90 $ 359.95
$ 1.33 per pill
Buy
Cialis
Tadalafil
10 mg x 180 pills
$ 284.90 $ 270.95
$ 1.51 per pill
Buy
Cialis
Tadalafil
10 mg x 120 pills
$ 205.90 $ 194.95
$ 1.62 per pill
Buy
Cialis
Tadalafil
10 mg x 90 pills
$ 186.90 $ 176.95
$ 1.97 per pill
Buy
Cialis
Tadalafil
10 mg x 60 pills
$ 143.90 $ 135.95
$ 2.27 per pill
Buy
Cialis
Tadalafil
10 mg x 30 pills
$ 83.90 $ 78.95
$ 2.63 per pill
Buy
Cialis
Tadalafil
10 mg x 20 pills
$ 62.90 $ 58.95
$ 2.95 per pill
Buy
Cialis
Tadalafil
10 mg x 10 pills
$ 35.90 $ 32.95
$ 3.30 per pill
Buy

Information

Effect of other drugs on Cialis Online San Marino

Cialis Uae is mainly metabolized with the participation of the CYP3A4 isoenzyme. Selective inhibitor of CYP3A4, ketoconazole (400 mg/day) increases the AUC of Buy Cialis In Makati in a single dose by 312% and SMACNA 22%, and ketoconazole (200 mg/day) increases the AUC of Cialis Uae in a single dose by 107% and Smachna 15% relative to the AUC values for Can You Buy Cialis Over The Counter Canada Smartelco one. Ritonavir (200 mg 2 times a day), an inhibitor of isoenzymes CYP3A4, 2C9, 2C19 and 2D6, increases the AUC of Cialis Online Italia Consegna Veloce in a single dose by 124% without changing Cmax. Although no specific interactions have been studied, it can be assumed that other HIV protease inhibitors such as saquinavir and CYP3A4 isoenzyme inhibitors such as erythromycin and Itraconazole increase Cialis Uae activity.

Selective inducer of CYP3A4, rifampin (600 mg/day), reduces the exposure of a single dose of Cialis Uae (AUC) by 88% and SMACNA 46% relative to the AUC values for Cialis Uae Smartelco one. It can be assumed that the simultaneous use of other inducers of CYP3A4 isoenzyme should also reduce the concentration of Cialis Uae in plasma.

Simultaneous administration of antacid (magnesium hydroxide/aluminum hydroxide) and Cialis Uae reduces the rate of absorption of Comprar Cialis Online Canada without changing the area under the pharmacokinetic curve for Cialis Uae. The increase in gastric pH as a result of the H2-histamine receptor blocker nizatidine had no effect on the pharmacokinetics of Cialis Uae.

The safety and effectiveness of the combination of Buy Cialis Over The Counter In Canada with other types of treatment of erection disorders have not been studied, so the use of such combinations is not recommended.

Comprar Cialis Online Canada does not potentiate the increase in bleeding time caused by taking acetylsalicylic acid.

Clinical pharmacology

Cialis Uae is a reversible selective inhibitor of specific PDE-5 cGMP. When sexual arousal causes local release of nitric oxide, inhibition of PDE-5 by Cialis Uae leads to an increase in the concentration of cGMP in the cavernous body of the penis. The consequence of this is the relaxation of the smooth muscles of the arteries and blood flow to the tissues of the penis, which causes an erection. Cialis Uae has no effect in the absence of sexual arousal.

In vitro studies have shown that Cialis Uae is a selective PDE-5 inhibitor. PDE-5 is an enzyme found in the smooth muscles of the cavernous body, in the smooth muscles of the vessels of the internal organs, in skeletal muscles, platelets, kidneys, lungs and cerebellum. The effect of Cialis Uae on PDE-5 is more active than on other PDES. Cialis Uae is 10,000 times more powerful against PDE-5 than against PDE-1, PDE-2, PDE-4 and PDE-7, which are localized in the heart, brain, blood vessels, liver, leukocytes, skeletal muscles and other organs. Cialis Uae is 10,000 times more active in blocking PDE-5 than PDE-3, an enzyme that is found in the heart and blood vessels. This selectivity for PDE-5 versus PDE-3 is important because PDE-3 is an enzyme involved in cardiac muscle contraction. In addition, Cialis Uae is approximately 700 times more active against PDE-5 than against PDE-6, which is found in the retina and is responsible for photo transmission. Cialis Uae is also showing the action in 9000 times more potent against PDE-5 compared with its effect on PDE-8, PDE-9, PDE-10 and 14 times more potent against PDE-5 compared to PDE-11. Tissue distribution and physiological effects of PDE-8 — PDE-11 inhibition have not yet been clarified.

Cialis 10mg Price In Uae improves erection and increases the possibility of a full sexual intercourse.

Cialis Uae in healthy individuals does not cause a significant change in sad and dad in comparison with placebo in the supine position (the average maximum decrease is 1.6/0.8 mm Hg. art respectively) and standing (mean maximum decrease of 0.2/4.6 mm Hg. art., respectively). Cialis Uae does not cause a significant change in heart rate.

Cialis Uae does not cause changes in color recognition (blue/green), due to the low affinity for PDE-6. In addition, there is no effect of Cialis Uae on visual acuity, electroretinogram, intraocular pressure and pupil size.

Clinical pharmacology

Several studies have been conducted to assess the effect of daily Cialis Uae on spermatogenesis. None of the studies showed an undesirable effect on the morphology of sperm and their mobility. One study found a decrease in the average sperm concentration compared to placebo. A decrease in sperm concentration was associated with a higher ejaculation rate. In addition, there was no undesirable effect on the average concentration of sex hormones, testosterone, LH and FSH when taking Cialis Uae compared to placebo.

The efficacy and safety of Cialis Uae (at doses of 2.5 mg and 5 mg) was studied in clinical trials. There was an improvement in erection in patients with erectile dysfunction of all degrees of severity when taking Cialis Uae 1 time per day. In studies of the primary efficacy of Cialis Online San Marino at a dose of 5 mg, 62% and 69% of sexual intercourse attempts were successful compared to 34% and 39% of placebo patients. Taking Cialis Farmacia Online España at a dose of 5 mg significantly improved erectile function for 24 hours between doses.

The mechanism of action of Cialis Uae in patients with BPH — inhibition of PDE-5 Buy Cialis Over The Counter Usa, leading to an increase in the concentration of cGMP in the cavernous body of the penis, is also observed in the smooth muscles of the prostate, bladder and blood vessels that supply them. Relaxation of the smooth muscles of the vessels leads to an increase in blood perfusion in these organs and as a consequence — to reduce the severity of symptoms of BPH. Relaxation of the smooth muscles of the prostate and bladder can further enhance vascular effects.

The use of Cialis Uae Cialis In Uae according to ED.For patients with frequent sexual activity (more than 2 times a week): the recommended frequency of intake is daily, 1 time per day 5 mg, at the same time, regardless of food intake. The daily dose may be reduced to 2.5 mg depending on individual sensitivity.

For patients with infrequent sexual activity (at least 2 times a week): it is recommended to prescribe Cialis Uae at a dose of 20 mg, immediately before sexual activity, according to the instructions for medical use of Cialis Uae. The maximum daily dose of Cialis Uae is 20 mg.

The use of Cialis Uae Cialis Uae for indication of BPH or ED/BPH.The recommended dose of Cialis Uae when used once a day is 5 mg; Cialis Uae should be taken at approximately the same time of day, regardless of the time of sexual activity. The duration of treatment is set by the doctor individually. In patients with renal insufficiency of mild severity (creatinine Cl from 51 to 80 ml/min) and moderate severity (creatinine Cl from 31 to 50 ml/min) dose adjustment is not required.

In patients with severe renal insufficiency (Creatinine CL <30 ml/min and hemodialysis):the use of Cialis Uae once a day is not recommended.

Pharmacokinetics

The pharmacokinetics of Cialis Uae in patients with erectile dysfunction is similar to the pharmacokinetics of Cialis Kupovina Online in persons without erectile dysfunction. Absorption After taking Cialis Uae inside Buy Cialis Over The Counter Uk is rapidly absorbed. The average plasma Cmax is achieved in an average of 2 hours after ingestion. The rate and degree of absorption of Can You Buy Cialis Over The Counter Uk does not depend on the meal, so Cialis Uae can be used regardless of the meal. The time of administration (morning or evening) had no clinically significant effect on the rate and degree of absorption. The pharmacokinetics of Cialis 20mg Price In Uae in healthy individuals is linear in terms of time and dose. In the dose range from 2.5 to 20 mg AUC increases in proportion to the dose. The distribution of Css in plasma is achieved within 5 days when taking Cialis Uae 1 time/day. The average Vd is about 63 liters, which indicates that Buy Cialis Miami is distributed in the tissues of the body. The plasma protein binding of Cialis Uae at therapeutic concentrations 94%. In healthy individuals, less than 0.0005% of the administered dose was found in sperm. Metabolism Cialis Generico Online Italia is mainly metabolized with the participation of CYP3A4 isoenzyme. The major circulating metabolite is methylethanolamine. This metabolite is at least 13,000 times less active against PDE5 than Cialis Uae. Therefore, the concentration of this metabolite is not clinically significant. Excretion In healthy individuals, the average clearance of Cialis Uae when administered is 2.5 l/h, and the average T1/2 - 17.5 h. Cialis Uae is excreted mainly in the form of inactive metabolites, mainly with feces (about 61% of the dose) and, to a lesser extent, with urine (about 36% of the dose). Pharmacokinetics in special clinical cases, protein Binding does not change with impaired renal function. Healthy elderly patients (65 years and more) had a lower clearance of Cialis Uae when administered, which was expressed in an increase in AUC by 25% compared with healthy individuals aged 19 to 45 years. This difference is not clinically significant and does not require dose adjustment. In patients with renal insufficiency of mild to moderate severity dose adjustment is not required. Due to the increased exposure of Cialis Uae (AUC), patients with severe renal insufficiency are not recommended to use Comprar Cialis Online Entrega 24 Horas. The pharmacokinetics of Cialis Uae in patients with weak and moderate hepatic insufficiency is comparable to that in healthy individuals In patients with severe hepatic insufficiency (class C according to the child-Pugh classification) data are not available. When prescribing Cialis Uae to patients with severe liver failure, it is necessary to pre-assess the risk and benefit of using Cialis Uae. In patients with diabetes mellitus during the use of Buy Cialis Denmark AUC was less by about 19% than in healthy individuals. This difference does not require dose selection.

Buy Cialis Miami

Our bestsellers