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Cialis Super Active Online Australia is mainly metabolized with the participation of the CYP3A4 isoenzyme. Selective inhibitor of CYP3A4, ketoconazole (400 mg/day) increases the AUC of Cialis Super Active Online Australia in a single dose by 312% and SMACNA 22%, and ketoconazole (200 mg/day) increases the AUC of Cialis Super Active Online Australia in a single dose by 107% and Smachna 15% relative to the AUC values for Cialis Super Active Online Australia Smartelco one. Ritonavir (200 mg 2 times a day), an inhibitor of isoenzymes CYP3A4, 2C9, 2C19 and 2D6, increases the AUC of Cialis Super Active Online Australia in a single dose by 124% without changing Cmax. Although no specific interactions have been studied, it can be assumed that other HIV protease inhibitors such as saquinavir and CYP3A4 isoenzyme inhibitors such as erythromycin and Itraconazole increase Cialis Super Active Online Australia activity.


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The active substance of Cialis Uae Price is Cialis Uae Price, which contributes to the inhibition of the production of the enzyme phosphodiesterase type 5 (PDE5). The enzyme (PDE5) regulates the concentration of cGMP (cyclic guanosine monophosphate) in the smooth muscles of the penis's tricky body.

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The duration of the generic Cialis Uae Price reaches 36 hours, but it is recommended to take a 20mg tablet 30 minutes before the intended sexual intercourse. Drink Cialis Uae Price should be water.

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Dosage and administration

Inside. Use of Can You Buy Cialis Over The Counter Cialis Uae Price according to the indication of erectile dysfunction (ED). For patients with frequent sexual activity (more than 2 times a week): the recommended frequency of intake is daily, 1 time per day 5 mg, at the same time, regardless of food intake. The daily dose can be reduced to 2.5 mg, depending on individual sensitivity. For patients with infrequent sexual activity (at least 2 times a week): it is recommended to prescribe Cialis Uae Price at a dose of 20 mg, immediately before sexual activity, according to the instructions for medical use of Cialis Online Kaufen Erfahrungen. The maximum daily dose of Buy Cialis Johannesburg is 20 mg. the Use of Cialis Uae Price according to the indication of BPH or ED/BPH. The recommended dose of Cialis Uae Price when used once a day is 5 mg; Cialis Uae Price should be taken at approximately the same time of day, regardless of the time of sexual activity. The duration of treatment is set by the doctor individually. In patients with mild renal insufficiency (creatinine Cl from 51 to 80 ml/min) and moderate (creatinine Cl from 31 to 50 ml/min) dose adjustment is not required. In patients with severe renal failure (Creatinine CL <30 ml/min and hemodialysis): use of Cialis Uae Price is contraindicated.

Side effect

Most often: headache, dyspepsia. Possible: back pain, myalgia, nasal congestion, blood flow to the face. Rarely: swelling of the eyelids, pain in the eyes, conjunctival hyperemia, dizziness.

Overdose

Symptoms: with a single appointment to healthy individuals Cialis Uae Price at a dose of up to 500 mg and patients with erectile dysfunction - repeatedly up to 100 mg/day, the undesirable effects were the same as when using Cialis Uae Price in lower doses. Treatment: in case of overdose, standard symptomatic treatment is necessary. In hemodialysis Cialis Uae Price practically displayed.

Interaction with other drugs

Cialis Uae Price is mainly metabolized by the enzyme CYP3A4. Selective inhibitor CYP3A4 ketoconazole increases AUC by 107%, and rifampicin reduces it by 88%. Although specific interactions have not been studied, it can be assumed that protease inhibitors such as ritonavir and saquinavir, as well as CYP3A4 inhibitors such as erythromycin and Itraconazole, increase the activity of Buy Cialis In Makati. The simultaneous administration of antacid (magnesium hydroxide/aluminium hydroxide) and Cialis Uae Price reduced the rate of absorption of the latter without changing the AUC. Cialis Online Kaufen Forum enhances the hypotensive effect of nitrates. This is due to the additive effect of nitrates and Cialis Uae Price on the metabolism of nitric oxide and cGMP. Therefore, the use of Cialis Uae Price in patients receiving nitrates is contraindicated

Effect of Cialis Uae Price on other drugs

It is known that Cialis Uae Price increases the hypotensive effect of nitrates. This is due to the additive effect of nitrates and Cialis Online Kaufen Ohne Rezept on the metabolism of nitric oxide (NO) and cGMP. Therefore, the use of Buy Cialis Medication in patients receiving nitrates is contraindicated.

Cialis Uae Price does not have a clinically significant effect on the clearance of drugs whose metabolism occurs with the participation of cytochrome P450. Studies have confirmed that Cialis Uae Price does not inhibit or induce isoenzymes CYP1A2, CYP3A4, CYP2C9, CYP2C19, CYP2D6, CYP2E1.

Cialis Uae Price does not have a clinically significant effect on the pharmacokinetics of S-warfarin or R-warfarin. Cialis Uae Price does not affect the action of warfarin against PV.

Cialis Uae Price does not increase the duration of bleeding caused by acetylsalicylic acid.

Cialis Tablets In Uae has systemic vasodilating properties and can enhance the effect of antihypertensive drugs aimed at reducing blood PRESSURE.

In addition, patients who took several antihypertensive drugs, in which hypertension was poorly controlled, there was a slightly greater decrease in blood PRESSURE. In the vast majority of patients, this decrease was not associated with hypotensive symptoms. Patients receiving treatment with antihypertensive drugs and taking Cialis Uae Price should be given appropriate clinical recommendations.

Did not observed a significant reduction in blood pressure in the application of Cialis Uae Price in healthy individuals taking selective альфа1А-blocker tamsulosin on the results of two clinical studies.

Coadministration of Cialis Uae Price with doxazosin is contraindicated. When using Viagra Cialis Vendita Online healthy volunteers, taking doxazosin (4-8 mg/day), alfa1-adrenoblokator, there was an increase in the hypotensive effect of doxazosin. Some patients experienced symptoms associated with a decrease in blood PRESSURE, including fainting.

Buy Cialis Taiwan did not affect the concentration of alcohol, nor did alcohol affect the concentration of Cialis Uae Price. At high doses of alcohol (0.7 g/kg), Cialis Uae Price did not cause a statistically significant decrease in the average blood PRESSURE. Some patients had postural dizziness and orthostatic hypotension. When taking Cialis Online Kaufen Ohne Rezept in combination with lower doses of alcohol (0.6 g/kg), a decrease in blood PRESSURE was not observed, and dizziness arose with the same frequency as when taking one alcohol.

Cialis Uae Price has no clinically significant effect on the pharmacokinetics or pharmacodynamics of theophylline.

Recommendations and contraindications

Be sure to consult your doctor before taking Cialis Malaysia Where To Buy pills. Based on your medical history, it will determine the risks you may be exposed to after taking the medicine. Here are the most important rules to follow:

  • Like any other drug of this action, Cialis 5mg Price In Uae is contraindicated in combination with nitrates (which are in medicines for the treatment of cardiovascular diseases).
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  • Hypertension, hepatic or renal failure, disorders of the heart-are one of the most important contraindications for the use of Cialis Uae Price.

Side effects and overdose

Due to the well-studied experience of Cialis Uae Price, side effects are quite rare. But there are exceptions to the rule, so you need to be prepared for the following symptoms:

  • Mild headaches
  • Dizziness and vomiting
  • A rush of blood to the face
  • Nasal congestion

When overdosed, the risk of getting one of the side effects increases. Therefore, you should immediately consult a doctor to conduct standard symptomatic therapy.

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