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Information

Clinical pharmacology

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The mechanism of action of Cialis Tablets In Uae in patients with BPH — inhibition of PDE-5 Cialis Tablets In Uae, leading to an increase in the concentration of cGMP in the cavernous body of the penis, is also observed in the smooth muscles of the prostate, bladder and blood vessels that supply them. Relaxation of the smooth muscles of the vessels leads to an increase in blood perfusion in these organs and as a consequence — to reduce the severity of symptoms of BPH. Relaxation of the smooth muscles of the prostate and bladder can further enhance vascular effects.

The use of Cialis Tablets In Uae Cialis Tablets In Uae according to ED.For patients with frequent sexual activity (more than 2 times a week): the recommended frequency of intake is daily, 1 time per day 5 mg, at the same time, regardless of food intake. The daily dose may be reduced to 2.5 mg depending on individual sensitivity.

For patients with infrequent sexual activity (at least 2 times a week): it is recommended to prescribe Cialis Ireland To Buy at a dose of 20 mg, immediately before sexual activity, according to the instructions for medical use of Cialis Tablets In Uae. The maximum daily dose of Cialis Online Kopen Nederland is 20 mg.

The use of Cialis Tablets In Uae Cialis Tablets In Uae for indication of BPH or ED/BPH.The recommended dose of Cialis Tablets In Uae when used once a day is 5 mg; Buy Cialis Denmark should be taken at approximately the same time of day, regardless of the time of sexual activity. The duration of treatment is set by the doctor individually. In patients with renal insufficiency of mild severity (creatinine Cl from 51 to 80 ml/min) and moderate severity (creatinine Cl from 31 to 50 ml/min) dose adjustment is not required.

In patients with severe renal insufficiency (Creatinine CL <30 ml/min and hemodialysis):the use of Cialis Tablets In Uae once a day is not recommended.

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The effect on the body Cialis Tablets In Uae is similar to Viagra and similar drugs, but there are some significant differences. For example, the action of Cialis Online Kopen Nederland is based on the properties of Cialis Tablets In Uae, which affects blood circulation in the pelvic organs, and the work of this substance continues for 36 hours, which is a record for today (for comparison: the duration of viagra is about 6 hours).

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Many men want to buy generic Cialis Tablets In Uae, not viagra, as in parallel with taking the pill you can drink alcohol and eat (even fat) without any health consequences. In addition, Cialis Online Bestellen Erfahrungsberichte does not serve as a reason for excitement, but only normalizes erectile function, allowing men to lead a full sexual life.

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Clinical pharmacology

Cialis Tablets In Uae is a reversible selective inhibitor of specific PDE-5 cGMP. When sexual arousal causes local release of nitric oxide, inhibition of PDE-5 by Cialis Generico Online Italia Consegna Veloce leads to an increase in the concentration of cGMP in the cavernous body of the penis. The consequence of this is the relaxation of the smooth muscles of the arteries and blood flow to the tissues of the penis, which causes an erection. Cialis Tablets In Uae has no effect in the absence of sexual arousal.

In vitro studies have shown that Cialis Tablets In Uae is a selective PDE-5 inhibitor. PDE-5 is an enzyme found in the smooth muscles of the cavernous body, in the smooth muscles of the vessels of the internal organs, in skeletal muscles, platelets, kidneys, lungs and cerebellum. The effect of Cialis Tablets In Uae on PDE-5 is more active than on other PDES. Cialis Tablets In Uae is 10,000 times more powerful against PDE-5 than against PDE-1, PDE-2, PDE-4 and PDE-7, which are localized in the heart, brain, blood vessels, liver, leukocytes, skeletal muscles and other organs. Cialis Tablets In Uae is 10,000 times more active in blocking PDE-5 than PDE-3, an enzyme that is found in the heart and blood vessels. This selectivity for PDE-5 versus PDE-3 is important because PDE-3 is an enzyme involved in cardiac muscle contraction. In addition, Comprar Cialis Online Mexico is approximately 700 times more active against PDE-5 than against PDE-6, which is found in the retina and is responsible for photo transmission. Cialis Tablets In Uae is also showing the action in 9000 times more potent against PDE-5 compared with its effect on PDE-8, PDE-9, PDE-10 and 14 times more potent against PDE-5 compared to PDE-11. Tissue distribution and physiological effects of PDE-8 — PDE-11 inhibition have not yet been clarified.

Cialis Tablets In Uae improves erection and increases the possibility of a full sexual intercourse.

Cialis Tablets In Uae in healthy individuals does not cause a significant change in sad and dad in comparison with placebo in the supine position (the average maximum decrease is 1.6/0.8 mm Hg. art respectively) and standing (mean maximum decrease of 0.2/4.6 mm Hg. art., respectively). Cialis Tablets In Uae does not cause a significant change in heart rate.

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About Cialis Tablets In Uae

Cialis Tablets In Uae is a drug that has long gained popularity in men who have a weak or unstable erection. A huge number of clinical studies and experiments were conducted, in which several thousand people with erectile dysfunction participated. The effectiveness of Cialis Tablets In Uae was 81%, this percentage of men was able to fully restore the "normal" erection, the rest got rid of their ailments, depending on the degree of complexity of the disease. Agree, this is an amazing result!

The main feature of Cialis Tablets In Uae is the ability to restore an erection for 36 hours after taking the pill, which will occur only with sexual arousal. That allows partners not to adapt to a certain time of Cialis Tablets In Uae, and lead a normal life before the natural desire. In addition, the effectiveness of Can You Buy Cialis Over The Counter will not affect a hearty dinner or drunk alcohol, which is also a definite plus for men of any age.

Action of preparation

We all understand that the main effect of the action of Cialis Tablets In Uae should be only one – increasing potency in men. This is exactly what happens after the use of Cialis Tablets In Uae, with sexual arousal: the blood vessels of the penis expand, after which it receives a more enhanced blood flow, thereby creating a "normal" erection. A noticeable improvement in potency can be observed within 20 minutes after the use of Cialis Online Kaufen Erfahrungen.

Application and dosage

Tablets are used inside and washed down with water, regardless of the meal. The minimum time before presumable sexual intercourse has to make 20 minutes. Most often, doctors recommend a dose of 20 mg. After that, for 36 hours, you can at any moment be in full sexual readiness. The maximum frequency of admission should not exceed 1 time per day. For the elderly, no changes in the dosage and application does not exist.

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