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Cialis (tadalafil)

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Cialis Online Kaufen österreich for the treatment of erectile dysfunction. Cialis Online Kaufen österreich is a reversible selective inhibitor of cyclic guanosine monophosphate (cGMP) PDE5. When sexual arousal causes local release of nitric oxide, inhibition of PDE5 by Cialis Online Kaufen österreich leads to an increase in the concentration of cGMP in the cavernous body of the penis. The consequence of this is the relaxation of the smooth muscles of the arteries and blood flow to the tissues of the penis, which causes an erection. Cialis Online Kaufen österreich has no effect in the absence of sexual arousal.


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Information

Dosage and administration

Inside. Use of Cialis 20mg Uae Cialis 20mg Uae according to the indication of erectile dysfunction (ED). For patients with frequent sexual activity (more than 2 times a week): the recommended frequency of intake is daily, 1 time per day 5 mg, at the same time, regardless of food intake. The daily dose can be reduced to 2.5 mg, depending on individual sensitivity. For patients with infrequent sexual activity (at least 2 times a week): it is recommended to prescribe Cialis Kaufen Online Rezeptfrei at a dose of 20 mg, immediately before sexual activity, according to the instructions for medical use of Cialis 20mg Uae. The maximum daily dose of Cialis Farmacia Online España is 20 mg. the Use of Cialis 20mg Uae according to the indication of BPH or ED/BPH. The recommended dose of Buy Cialis Over The Counter Usa when used once a day is 5 mg; Cialis 20mg Uae should be taken at approximately the same time of day, regardless of the time of sexual activity. The duration of treatment is set by the doctor individually. In patients with mild renal insufficiency (creatinine Cl from 51 to 80 ml/min) and moderate (creatinine Cl from 31 to 50 ml/min) dose adjustment is not required. In patients with severe renal failure (Creatinine CL <30 ml/min and hemodialysis): use of Cialis Online Italia Consegna Veloce is contraindicated.

Side effect

Most often: headache, dyspepsia. Possible: back pain, myalgia, nasal congestion, blood flow to the face. Rarely: swelling of the eyelids, pain in the eyes, conjunctival hyperemia, dizziness.

Overdose

Symptoms: with a single appointment to healthy individuals Comprar Cialis Online En Usa at a dose of up to 500 mg and patients with erectile dysfunction - repeatedly up to 100 mg/day, the undesirable effects were the same as when using Cialis 20mg Uae in lower doses. Treatment: in case of overdose, standard symptomatic treatment is necessary. In hemodialysis Cialis 20mg Uae practically displayed.

Interaction with other drugs

Cialis Online Miglior Prezzo is mainly metabolized by the enzyme CYP3A4. Selective inhibitor CYP3A4 ketoconazole increases AUC by 107%, and rifampicin reduces it by 88%. Although specific interactions have not been studied, it can be assumed that protease inhibitors such as ritonavir and saquinavir, as well as CYP3A4 inhibitors such as erythromycin and Itraconazole, increase the activity of Can I Buy Cialis Over The Counter Australia. The simultaneous administration of antacid (magnesium hydroxide/aluminium hydroxide) and Cialis 20mg Uae reduced the rate of absorption of the latter without changing the AUC. Cialis 20mg Uae enhances the hypotensive effect of nitrates. This is due to the additive effect of nitrates and Cialis 20mg Uae on the metabolism of nitric oxide and cGMP. Therefore, the use of Cialis 20mg Uae in patients receiving nitrates is contraindicated

Effect of other drugs on Cialis 20mg Uae

Cialis 20mg Uae is mainly metabolized with the participation of the CYP3A4 isoenzyme. Selective inhibitor of CYP3A4, ketoconazole (400 mg/day) increases the AUC of Cialis 20mg Uae in a single dose by 312% and SMACNA 22%, and ketoconazole (200 mg/day) increases the AUC of Cialis 20mg Uae in a single dose by 107% and Smachna 15% relative to the AUC values for Cialis 20mg Uae Smartelco one. Ritonavir (200 mg 2 times a day), an inhibitor of isoenzymes CYP3A4, 2C9, 2C19 and 2D6, increases the AUC of Cialis 20mg Uae in a single dose by 124% without changing Cmax. Although no specific interactions have been studied, it can be assumed that other HIV protease inhibitors such as saquinavir and CYP3A4 isoenzyme inhibitors such as erythromycin and Itraconazole increase Cialis 20mg Uae activity.

Selective inducer of CYP3A4, rifampin (600 mg/day), reduces the exposure of a single dose of Cialis 20mg Uae (AUC) by 88% and SMACNA 46% relative to the AUC values for Cialis 20mg Uae Smartelco one. It can be assumed that the simultaneous use of other inducers of CYP3A4 isoenzyme should also reduce the concentration of Cialis 20mg Uae in plasma.

Simultaneous administration of antacid (magnesium hydroxide/aluminum hydroxide) and Buy Cialis Taiwan reduces the rate of absorption of Cialis 20mg Uae without changing the area under the pharmacokinetic curve for Cialis 20mg Uae. The increase in gastric pH as a result of the H2-histamine receptor blocker nizatidine had no effect on the pharmacokinetics of Comprar Cialis Online En Usa.

The safety and effectiveness of the combination of Cialis 20mg Uae with other types of treatment of erection disorders have not been studied, so the use of such combinations is not recommended.

Cialis 20mg Uae does not potentiate the increase in bleeding time caused by taking acetylsalicylic acid.

Clinical pharmacology

Several studies have been conducted to assess the effect of daily Cialis 20mg Uae on spermatogenesis. None of the studies showed an undesirable effect on the morphology of sperm and their mobility. One study found a decrease in the average sperm concentration compared to placebo. A decrease in sperm concentration was associated with a higher ejaculation rate. In addition, there was no undesirable effect on the average concentration of sex hormones, testosterone, LH and FSH when taking Cialis 20mg Uae compared to placebo.

The efficacy and safety of Cialis 20mg Uae (at doses of 2.5 mg and 5 mg) was studied in clinical trials. There was an improvement in erection in patients with erectile dysfunction of all degrees of severity when taking Cialis Online Miglior Prezzo 1 time per day. In studies of the primary efficacy of Cialis 20mg Uae at a dose of 5 mg, 62% and 69% of sexual intercourse attempts were successful compared to 34% and 39% of placebo patients. Taking Cialis 20mg Uae at a dose of 5 mg significantly improved erectile function for 24 hours between doses.

The mechanism of action of Cialis 20mg Uae in patients with BPH — inhibition of PDE-5 Cialis 20mg Uae, leading to an increase in the concentration of cGMP in the cavernous body of the penis, is also observed in the smooth muscles of the prostate, bladder and blood vessels that supply them. Relaxation of the smooth muscles of the vessels leads to an increase in blood perfusion in these organs and as a consequence — to reduce the severity of symptoms of BPH. Relaxation of the smooth muscles of the prostate and bladder can further enhance vascular effects.

The use of Cialis 20mg Uae Cialis Buy South Africa according to ED.For patients with frequent sexual activity (more than 2 times a week): the recommended frequency of intake is daily, 1 time per day 5 mg, at the same time, regardless of food intake. The daily dose may be reduced to 2.5 mg depending on individual sensitivity.

For patients with infrequent sexual activity (at least 2 times a week): it is recommended to prescribe Cialis 20mg Uae at a dose of 20 mg, immediately before sexual activity, according to the instructions for medical use of Cialis 20mg Uae. The maximum daily dose of Cialis 20mg Uae is 20 mg.

The use of Cialis 20mg Uae Cialis 20mg Uae for indication of BPH or ED/BPH.The recommended dose of Cialis Online Kopen Ervaringen when used once a day is 5 mg; Cialis 20mg Uae should be taken at approximately the same time of day, regardless of the time of sexual activity. The duration of treatment is set by the doctor individually. In patients with renal insufficiency of mild severity (creatinine Cl from 51 to 80 ml/min) and moderate severity (creatinine Cl from 31 to 50 ml/min) dose adjustment is not required.

In patients with severe renal insufficiency (Creatinine CL <30 ml/min and hemodialysis):the use of Cialis 20mg Uae once a day is not recommended.

Recommendations and contraindications

Be sure to consult your doctor before taking Cialis 20mg Uae pills. Based on your medical history, it will determine the risks you may be exposed to after taking the medicine. Here are the most important rules to follow:

  • Like any other drug of this action, Cialis 20mg Uae is contraindicated in combination with nitrates (which are in medicines for the treatment of cardiovascular diseases).
  • The body, which is sensitive to any of the components of Cialis 20mg Uae, Cialis 20mg Uae is strictly contraindicated.
  • It should not be used by persons under the age of 18.
  • Hypertension, hepatic or renal failure, disorders of the heart-are one of the most important contraindications for the use of Comprare Cialis Online è Legale.

Side effects and overdose

Due to the well-studied experience of Cialis 20mg Uae, side effects are quite rare. But there are exceptions to the rule, so you need to be prepared for the following symptoms:

  • Mild headaches
  • Dizziness and vomiting
  • A rush of blood to the face
  • Nasal congestion

When overdosed, the risk of getting one of the side effects increases. Therefore, you should immediately consult a doctor to conduct standard symptomatic therapy.

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